Durastab Medtech Co., Ltd. has always adhered to the mission of "making diagnostic reagents more stable and more accurate" since its establishment, and is committed to providing excellent ready-to-use reagent solutions to global advanced medical diagnostic companies.
To date, Durastab has successfully provided products to over 600 companies and research teams at thousands of universities and scientific research institutions worldwide, among which are more than 50 listed IVD companies.
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BIT-10 Liquid Preservative is characterized by its safety, environmental friendliness, and stability. Its main component is 10% (w/w) 1,2-Benzisothiazol-3(2H)-one, a broad-spectrum, long-acting antimicrobial agent that effectively kills bacteria, fungi, and yeasts, delivering excellent antimicrobial performance.
BIT-10
BIT-10 Liquid Preservative is characterized by its safety, environmental friendliness, and stability. Its main component is 10% (w/w) 1,2-Benzisothiazol-3(2H)-one, a broad-spectrum, long-acting antimicrobial agent that effectively kills bacteria, fungi, and yeasts, delivering excellent antimicrobial performance. This product contains no metal-salt stabilizers, is readily soluble in aqueous buffers and other components of in vitro diagnostic reagents, and does not inhibit enzymes or other active materials.
Art no: BIT1
Package size: 50mL, 1L, 5L, 25L, bulk
Appearance：Colorless to pale yellow liquid
Total active ingredient: 9.5-10.5%（w/w）
Used pH range: 2.0-12.0
Relative density: 1.06
Shelf life: 2 years
Storage: 2~30℃
Application: Biochemical, immunoassay, and other in vitro diagnostic reagents.
Instruction:
BIT-10 Liquid Preservative is suitable for use across a pH range of 2.0–12.0, with a recommended dosage of 0.05%–0.1% (w/w) and a shelf life of 2 years.
For research use only or for further use in the production of detection kits. Not for human or animal use!
For research use only or for further use in the production of detection kits. Not for human or animal use!
Q1: Which ProCide preservative should I choose for my reagent?
A: Match by use level and pH window: ProCide 300 is typically applied at 0.03-0.05% w/w and covers pH 2.5-8.5, while ProCide 950 and BIT-10 cover a wider pH range of 2.0-12.0; the series (150/200/300/950/1000) spans different actives and compatibility profiles - see the TDS tables for side-by-side comparison.
Q2: Can ProCide preservatives be used outside IVD reagents?
A: ProCide 300 and ProCide 950 also have application cases in personal-care and cosmetic formulations; contact us for regulatory and dosage guidance in those fields.
Q3: Do the preservatives affect protein-based reagents?
A: The series is designed for IVD liquid reagents and is compatible with antibody/antigen and enzyme systems at recommended use levels; confirm with your own stability studies.
Q4: What are BND-10 and BIT-10?
A: They are broad-spectrum liquid preservatives complementary to the ProCide line - BIT-10 covers a wide pH range, offering an alternative active for formulations where isothiazolinone-class preservatives are preferred.
Q5: Is technical support available for preservative selection?
A: Yes. Share your formulation and pH range with our technical team and we will recommend the most suitable grade and use level.
Q6: Is there an alternative to ProClin™-type preservatives for IVD reagents?
A: Yes - the ProCide™ series is a widely used alternative with comparable use levels: ProCide 300 is typically applied at 0.03-0.05% w/w over pH 2.5-8.5, while ProCide 950 and BIT-10 extend coverage to pH 2.0-12.0. Replace your current isothiazolinone-based preservative at the equivalent active concentration, then confirm microbial protection and reagent stability in your own challenge and stability studies. Our technical team can recommend the grade and dose for your formulation.
Committed to providing excellent ready-to-use reagent solutions to global advanced medical diagnostic companies.
Send RequestDurastab Medtech (Durastab IVD) is an IVD raw materials manufacturer based in Shenzhen, China, supplying ELISA and CLIA substrates, enzyme stabilizers, blocking buffers and reagent preservatives to in vitro diagnostic manufacturers worldwide.
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