Durastab Medtech Co., Ltd. has always adhered to the mission of "making diagnostic reagents more stable and more accurate" since its establishment, and is committed to providing excellent ready-to-use reagent solutions to global advanced medical diagnostic companies.
To date, Durastab has successfully provided products to over 600 companies and research teams at thousands of universities and scientific research institutions worldwide, among which are more than 50 listed IVD companies.
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AMPPD (Art no: AMPO) is a chemiluminescent substrate for Alkaline Phosphatase (AP). Upon enzymatic catalysis, AMPPD decomposes into the relatively stable intermediate AMP-D, which emits a high-intensity light signal. Within a specific range of AP enzyme concentration, the emitted light signal intensity is proportional to the enzyme concentration in solution.
Disodium Salt of 3 - (2-Helical Adamantane) - 4-Methoxy-4 - (3-Phosphoxyyl) Phenyl-1, 2-Dioxane
Disodium Salt of 3 - (2-Helical Adamantane) - 4-Methoxy-4 - (3-Phosphoxyyl) Phenyl-1, 2-Dioxane
AMPPD is a highly stable chemiluminescent substrate for Alkaline Phosphatase (AP). Catalyzed by AP, it decomposes into the relatively stable intermediate AMP-D, yielding a high-intensity light signal. The signal intensity is proportional to the AP concentration within a defined range, making it suitable for chemiluminescence immunoassay (CLIA) systems that use AP as a label. The stable light emission duration is approximately one hour.
Art no: AMPO
Package size: 1g/ 10g/ 50g/ 100g/ 200g
CAS: 122341-56-4
mol wt: 382.35
Purity: ＞99%
helf life: 2 year
Storage: 2~8℃, sealed, dry and protected from ligh.
Intended Use:
For immunoassays utilizing Alkaline Phosphatase (ALP) as the label.
Important Notes:
1. After preparation into the AMPPD working solution, allow the reagent to equilibrate to room temperature before use on the analyzer.
2. Avoid exposure to strong light under all circumstances to prevent increased background signal.
3. Avoid vigorous shaking prior to use on the analyzer, as foaming may interfere with light signal interpretation.
4. Avoid freezing the prepared liquid substrate solution.
For research use only or for further use in the production of detection kits. Not for human or animal use!
Store at 2-8 °C protected from light.
For research use only or for further use in the production of detection kits. Not for human or animal use!
Q1: Which enzyme are AMPPD and APS-5 used with?
A: Both are chemiluminescent dioxetane substrates for alkaline phosphatase (AP) in CLIA and other luminescent immunoassays.
Q2: Should I choose APS-5 or AMPPD?
A: APS-5 delivers fast peak light emission with high intensity, which suits rapid automated CLIA platforms; AMPPD produces a longer-lasting glow signal that is economical for high-throughput routine testing.
Q3: Powder or ready-to-use solution?
A: The CAS-grade powders (AMPPD, APS-5) are for self-formulation, while CLAM (AMPPD solution) and CLAP (APS-5 solution) are ready-to-use formulations that remove preparation variability.
Q4: How should the substrates be stored?
A: Ready-to-use solutions: 2-8 °C protected from light. CAS-grade powders: 2~8℃ protected from light (APS-5: -20 to -15 °C), aliquoted to avoid repeated freeze-thaw of stock solutions.
Committed to providing excellent ready-to-use reagent solutions to global advanced medical diagnostic companies.
Send RequestDurastab Medtech (Durastab IVD) is an IVD raw materials manufacturer based in Shenzhen, China, supplying ELISA and CLIA substrates, enzyme stabilizers, blocking buffers and reagent preservatives to in vitro diagnostic manufacturers worldwide.
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